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KMID : 1123920080220051283
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Korean Journal of Oriental Physiology and Pathology
2008 Volume.22 No. 5 p.1283 ~ p.1292
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Effects of Iksugangjiryung on Hyperlipidemia in Rats
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Kim Jeung-Beum
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Abstract
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This study was designed to investigate the hyperlipidemia-healing effect of water extract from Iksukangjiryung, it was performed on the hyperlipidemia of rats induced by Triton WR-1339 and high cholesterol diet. We prepared two types of hyperlipidemia model in rats induced by Triton WR-1339 and high cholesterol diet. The amount of total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, lipid peroxide, glutathione and the activity of superoxide dismutase(SOD) were measured. The water extract from Iksukangjiryung showed significant decreasing effects on total cholesterol, LDL- cholesterol, triglyceride, lipid peroxide in the both model. And it showed significant increasing effects on the activity of SOD in both model and amount of glutathione in Triton WR-1339 model. These results suggest that water extract from Iksukangjiryung has healing efficacy on hyperlipidemia induced by Triton WR-1339 and high cholesterol diet.
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KEYWORD
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Iksukangjiryung, hyperlipidemia, total cholesterol, triglyceride
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